Identifying Genes

1989

Lap-Chee Tsui and Manuel Buchwald isolated the gene carrying the defect that causes cystic fibrosis, a disease characterized by the buildup of mucus that can damage many of the body’s organs. Its symptoms include frequent respiratory infections, as well as malnutrition and diabetes. People with cystic fibrosis often die young.

The University of Toronto geneticists’ 1989 discovery has led to improved treatments and better ways to manage the disease.

The Canadian Encyclopedia: Lap-Chee Tsui